About fluphenazine decanoate
Long-acting typical antipsychotic
Used for
- Maintenance treatment of schizophrenia and other psychotic disorders
Usual adult dose
Usually 12.5–25 mg injected into a muscle every 2–4 weeks; adjusted to response.
Common side effects
- Movement problems, including stiffness, tremor, or restlessness
- Sleepiness or dizziness
- Dry mouth, constipation, or blurred vision
- Injection-site pain
Important warnings
- Can cause potentially irreversible movement disorders, especially with long-term use.
- May cause severe muscle stiffness, fever, confusion, or unstable blood pressure.
- Increases risk of falls and heat-related illness; use caution in older adults.
- Not approved for dementia-related psychosis; may increase risk of death.
Pregnancy
Use during pregnancy only when clearly needed; exposure near delivery may cause newborn movement or withdrawal symptoms.
Breastfeeding
May pass into breast milk and affect the infant; discuss risks with a healthcare professional.
Interactions
- Alcohol, opioids, and sedatives can increase drowsiness and breathing problems.
- Medicines that prolong the QT interval can increase risk of abnormal heart rhythms.
- Levodopa and dopamine agonists may have reduced effects.
- Lithium can increase risk of confusion and movement problems.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.