About fluconazole
Triazole antifungal
Used for
- Treats Candida infections, including bloodstream and deep-tissue infections.
- Treats cryptococcal meningitis and helps prevent its recurrence.
- Prevents fungal infections in some people with weakened immunity.
Usual adult dose
Varies by infection: commonly 200–800 mg once daily intravenously; treatment duration depends on the condition.
Usual dose in children
Varies by infection: commonly 6–12 mg/kg once daily intravenously; maximum usually 400–800 mg daily, depending on indication.
Common side effects
- Nausea, abdominal pain, diarrhoea, or headache
- Raised liver enzymes
- Rash
- Rarely, serious liver injury or abnormal heart rhythm
Important warnings
- Dose adjustment may be needed with kidney impairment.
- Rarely causes severe liver problems or serious skin reactions.
- Can prolong the heart’s electrical rhythm; risk is higher with certain conditions or medicines.
- Some fungal infections require different treatment; diagnosis and susceptibility matter.
Pregnancy
Use during pregnancy only when clearly needed. Prolonged or high-dose treatment may harm the fetus; avoid for routine vaginal yeast infection.
Breastfeeding
Fluconazole enters breast milk. Short courses are generally considered compatible with breastfeeding; prolonged or high doses require clinical assessment.
Interactions
- Warfarin: may increase bleeding risk.
- Some statins: may increase muscle injury risk.
- Certain diabetes medicines: may cause low blood sugar.
- Some medicines affecting heart rhythm: increased risk of abnormal rhythm.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.