About floxuridine
Antimetabolite chemotherapy drug
Used for
- Given by hepatic-artery infusion for certain cancers that have spread to the liver, especially colorectal cancer.
Usual adult dose
Dosing is individualized and usually delivered by continuous hepatic-artery infusion under specialist supervision.
Common side effects
- Nausea or vomiting
- Diarrhea or mouth sores
- Liver injury
- Low blood counts and infection risk
Important warnings
- For specialist use; dosing and monitoring require an oncology team.
- Serious or fatal liver, gastrointestinal, and bone-marrow toxicity can occur.
- Avoid during pregnancy; it can harm an unborn baby.
- Report fever, bleeding, severe diarrhea, or yellowing skin promptly.
Pregnancy
Can cause fetal harm. Avoid during pregnancy; effective contraception is generally required during treatment.
Breastfeeding
Breastfeeding is not recommended during treatment because of potential serious harm to the infant.
Interactions
- Other chemotherapy or radiation may increase bone-marrow suppression and toxicity.
- Live vaccines may cause infection during immunosuppressive treatment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.