About finerenone
Nonsteroidal mineralocorticoid receptor antagonist
Used for
- Reduces kidney and cardiovascular risks in adults with chronic kidney disease associated with type 2 diabetes.
Usual adult dose
Usually 10 or 20 mg once daily, based on kidney function and blood potassium; may increase after four weeks.
Common side effects
- High blood potassium
- Low blood pressure
- Low sodium levels
- Reduced kidney function
Important warnings
- Check blood potassium and kidney function before treatment and during therapy.
- Do not use with strong CYP3A4 inhibitors or in Addison’s disease.
- Risk of high potassium increases with kidney problems and certain medicines.
Pregnancy
May harm a fetus based on animal studies; human pregnancy data are limited.
Breastfeeding
It is unknown whether finerenone passes into human milk; breastfeeding effects are unknown.
Interactions
- Strong CYP3A4 inhibitors can greatly increase finerenone levels.
- Strong or moderate CYP3A4 inducers can reduce its effect.
- Other medicines that raise potassium increase hyperkalemia risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.