About finerenon e
Nonsteroidal mineralocorticoid receptor antagonist
Used for
- Reduces risk of kidney disease worsening in adults with chronic kidney disease and type 2 diabetes.
- Reduces risk of cardiovascular events in adults with these conditions.
Usual adult dose
Usually 10 mg or 20 mg once daily, adjusted according to kidney function and blood potassium.
Common side effects
- High blood potassium
- Low blood pressure
- Low sodium
- Reduced kidney function
Important warnings
- Blood potassium and kidney function require monitoring.
- Do not use with strong CYP3A4 inhibitors or adrenal insufficiency.
- Avoid grapefruit and grapefruit juice.
- Dose may need adjustment with medicines that affect CYP3A4.
Pregnancy
Safety is not established; use during pregnancy only if clearly needed.
Breastfeeding
It is not known whether finerenone enters human milk; discuss risks and benefits with a healthcare professional.
Interactions
- Strong CYP3A4 inhibitors can greatly increase finerenone levels.
- CYP3A4 inducers can reduce its effect.
- Other medicines that raise potassium increase the risk of high blood potassium.
- Grapefruit may increase finerenone levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.