About filgrastim
Granulocyte colony-stimulating factor (G-CSF)
Used for
- Prevents or treats low neutrophil counts after chemotherapy
- Supports blood-cell recovery after bone marrow transplantation
- Mobilizes stem cells for collection
- Treats severe chronic neutropenia
Usual adult dose
Usually 5 micrograms/kg under the skin or into a vein daily; dose and duration depend on the condition and blood counts.
Usual dose in children
Used in children for similar indications; doses are weight-based, commonly 5 micrograms/kg daily, with specialist adjustment.
Common side effects
- Bone or muscle pain
- Low platelet count
- Injection-site reactions
- Headache
Important warnings
- Rare serious allergic reactions can occur.
- May cause enlargement or rupture of the spleen; seek urgent care for upper-left abdominal or shoulder pain.
- Serious lung inflammation and breathing problems are possible.
- Blood counts and spleen symptoms require monitoring.
Pregnancy
Human data are limited. Use during pregnancy only when clearly needed after weighing potential benefits and risks.
Breastfeeding
It is not known whether filgrastim passes into human milk; breastfeeding decisions depend on clinical circumstances.
Interactions
- Lithium may increase neutrophil production; blood counts need monitoring.
- Use caution with chemotherapy or radiotherapy because timing affects safety and effectiveness.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.