About filgrastim mu
Granulocyte colony-stimulating factor
Used for
- Prevention and treatment of low neutrophil counts after chemotherapy
- Support for blood stem-cell collection and transplantation
- Treatment of severe chronic neutropenia
- Treatment of neutropenia after bone-marrow transplantation
Usual adult dose
Depends on the condition and body weight; commonly 5 micrograms/kg under the skin or into a vein daily for chemotherapy-related neutropenia.
Usual dose in children
For chemotherapy-related neutropenia, commonly 5 micrograms/kg under the skin or into a vein daily; specialist dosing varies by condition.
Common side effects
- Bone or muscle pain
- Fever
- Headache
- Injection-site reactions
Important warnings
- Rarely, the spleen can enlarge or rupture; seek urgent care for sudden left upper abdominal or shoulder pain.
- Rarely, serious allergic reactions or breathing problems occur.
- Sickle-cell crises and severe lung inflammation have been reported.
- Blood counts require monitoring; dosing and timing depend on treatment.
Pregnancy
Human pregnancy data are limited; use only when the expected benefit outweighs potential risk.
Breastfeeding
It is unknown whether filgrastim enters breast milk; use requires clinical assessment.
Interactions
- Lithium may increase neutrophil production and affect blood counts.
- Use around chemotherapy or radiotherapy requires careful timing and monitoring.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.