About Fentanyl (matrix) 50mcg/h
Opioid analgesic
Used for
- Severe, persistent pain requiring continuous opioid treatment, when other pain medicines are inadequate.
Usual adult dose
Applied every 72 hours; dose is individualized and depends on previous opioid use. Opioid conversion requires specialist supervision.
Usual dose in children
For opioid-tolerant children aged 2 years and older: individualized dose, usually changed every 72 hours; specialist supervision required.
Common side effects
- Sleepiness, dizziness, headache
- Nausea, vomiting, constipation
- Itching, sweating, or skin irritation
- Slow or difficult breathing
Important warnings
- Can cause fatal breathing suppression, especially when starting or increasing treatment.
- Only for opioid-tolerant patients; not for sudden or occasional pain.
- Heat or fever can increase absorption and overdose risk.
- Keep securely away from children; used and unused patches can be fatal.
Pregnancy
Prolonged use during pregnancy may cause newborn withdrawal; use requires careful medical assessment.
Breastfeeding
Fentanyl enters breast milk and may cause infant sleepiness or breathing problems; breastfeeding is generally not recommended during treatment.
Interactions
- Alcohol, sleeping medicines, and other sedatives increase severe drowsiness and breathing risks.
- Some antibiotics, antifungals, and HIV medicines can raise fentanyl levels.
- Rifampicin, carbamazepine, and phenytoin can lower fentanyl levels.
- MAO inhibitors and serotonergic medicines may cause serious interactions.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.