About bempedoic acid + ezetimibe
Cholesterol-lowering medicines
Used for
- Lowers LDL (“bad”) cholesterol in adults with high cholesterol, alongside diet and other treatment.
- May help reduce cardiovascular risk in some adults with established heart disease.
Usual adult dose
One tablet by mouth once daily, with or without food; follow the prescribed regimen.
Common side effects
- Muscle aches or spasms
- Joint pain
- Raised uric acid or gout
- Diarrhea or abdominal discomfort
Important warnings
- May increase uric acid and trigger gout.
- Rarely, bempedoic acid can cause tendon injury or rupture.
- Liver enzyme increases can occur; muscle problems are possible, especially with certain medicines.
- Not suitable during pregnancy; cholesterol-lowering treatment is generally stopped during pregnancy.
Pregnancy
Avoid during pregnancy; treatment is generally discontinued when pregnancy is recognized because cholesterol-lowering benefit is not needed during pregnancy.
Breastfeeding
Breastfeeding is generally not recommended while taking this combination; discuss alternatives with a healthcare professional.
Interactions
- Bempedoic acid can raise levels of simvastatin and pravastatin, increasing muscle-injury risk.
- Ezetimibe with cyclosporine may increase levels of both medicines.
- Bile-acid sequestrants can reduce ezetimibe absorption; separate doses by at least two hours before or four hours after.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.