About evolocuma b
PCSK9 inhibitor monoclonal antibody
Used for
- Lowers LDL cholesterol in adults with cardiovascular disease or inherited high cholesterol.
- Lowers LDL cholesterol in some children with inherited high cholesterol.
- Reduces risk of heart attack and stroke in certain adults.
Usual adult dose
140 mg under the skin every two weeks, or 420 mg monthly; dose depends on condition.
Usual dose in children
For inherited high cholesterol, dosing depends on age and weight; specialist supervision is required.
Common side effects
- Runny nose, sore throat, or flu-like symptoms
- Back pain
- Injection-site reactions
- Allergic reactions, rarely severe
Important warnings
- Seek urgent care for swelling, breathing difficulty, or severe allergic symptoms.
- Check cholesterol response during treatment.
- Do not use with a serious allergy to evolocumab or its ingredients.
Pregnancy
Human pregnancy information is limited. Use during pregnancy only when clearly needed; discuss risks with a clinician.
Breastfeeding
It is unknown whether evolocumab passes into breast milk. Consider infant needs and treatment importance with a clinician.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.