About etanercep t
Tumor necrosis factor inhibitor
Used for
- Rheumatoid arthritis and juvenile idiopathic arthritis
- Psoriatic arthritis
- Ankylosing spondylitis
- Plaque psoriasis
Usual adult dose
Usually 50 mg under the skin once weekly; some conditions use 25 mg twice weekly.
Usual dose in children
For juvenile arthritis, usually 0.8 mg/kg under the skin weekly, maximum 50 mg.
Common side effects
- Injection-site redness, pain, or swelling
- Infections, including upper respiratory infections
- Headache
- Rash
Important warnings
- Serious infections, including tuberculosis, can occur; screening is needed before treatment.
- Avoid live vaccines during treatment.
- May worsen heart failure or cause rare nervous system disorders.
- Rarely associated with certain cancers and blood disorders.
Pregnancy
Available evidence has not shown a clear increase in major birth defects; use requires discussion of benefits and risks.
Breastfeeding
Etanercept levels in breast milk are expected to be low; infant effects are not well established.
Interactions
- Anakinra or abatacept: increased risk of serious infections; combination is generally avoided.
- Live vaccines: may cause infection during treatment.
- Cyclophosphamide: combination may increase cancer risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.