About estriol
Vaginal estrogen hormone
Used for
- Treats vaginal dryness, irritation, and pain from low estrogen after menopause.
Usual adult dose
Often 0.5 g vaginally daily initially, then reduced to twice weekly; follow the prescribed regimen.
Common side effects
- Vaginal irritation or itching
- Breast tenderness
- Headache
- Spotting or vaginal bleeding
Important warnings
- Unexplained vaginal bleeding needs evaluation.
- Avoid or seek specialist review with a history of estrogen-sensitive cancer or blood clots.
- Estrogen can rarely increase clot, stroke, or endometrial risks.
- Use the lowest effective dose for the shortest necessary duration.
Pregnancy
Not used during pregnancy; safety is not established.
Breastfeeding
Usually avoided while breastfeeding; estrogen may reduce milk supply.
Interactions
- Other estrogen medicines may increase estrogen-related effects.
- Medicines that induce liver enzymes, such as rifampicin, may reduce estrogen effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.