About estradiol valerate
Estrogen-progestogen hormone therapy
Used for
- Treatment of menopausal symptoms in women with a uterus
- Prevention of bone loss after menopause when other treatments are unsuitable
- Treatment of estrogen deficiency when ovaries do not function
Usual adult dose
One tablet daily in the prescribed 21-day sequence, followed by a seven-day break; the pack includes progestogen.
Common side effects
- Headache
- Breast tenderness
- Nausea or abdominal discomfort
- Irregular bleeding or spotting
Important warnings
- Not for pregnancy, unexplained vaginal bleeding, or current or previous breast cancer
- Avoid with previous or current blood clots, stroke, or serious liver disease
- Hormone therapy can increase risks of blood clots, stroke, and some cancers
- Seek prompt assessment for chest pain, breathlessness, or one-sided leg swelling
Pregnancy
Do not use during pregnancy; stop if pregnancy occurs.
Breastfeeding
Generally not recommended during breastfeeding; estrogen may reduce milk supply.
Interactions
- Some seizure medicines, rifampicin, and St John’s wort can reduce effects
- Some HIV or hepatitis medicines can alter hormone levels
- May affect blood sugar control and anticoagulant treatment
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.