About estradiol + norethindrone acetate
Estrogen-progestin hormone therapy
Used for
- Treats menopause symptoms such as hot flushes and night sweats
- Helps prevent osteoporosis after menopause in selected women
Usual adult dose
One tablet once daily for menopause symptoms or osteoporosis prevention.
Common side effects
- Headache
- Breast tenderness
- Nausea
- Irregular vaginal bleeding
Important warnings
- Can increase risks of blood clots, stroke, and certain cancers
- Unexplained vaginal bleeding should be evaluated before treatment
- Not for preventing heart disease or dementia
- Risk may be higher with smoking or prolonged treatment
Pregnancy
Not used during pregnancy; discontinue if pregnancy occurs.
Breastfeeding
Not recommended during breastfeeding.
Interactions
- Enzyme-inducing medicines such as carbamazepine may reduce hormone levels
- Some antiviral medicines can alter hormone levels
- St John’s wort may reduce effectiveness
- May affect medicines such as warfarin
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.