About estradiol hemihydra te
Topical estrogen hormone
Used for
- Relief of menopausal symptoms, such as hot flushes and night sweats
- Prevention of bone loss after menopause in selected people
Usual adult dose
Apply one measured pump daily to clean, dry skin; dose varies by symptoms and local product instructions.
Common side effects
- Breast tenderness or pain
- Headache
- Nausea or abdominal discomfort
- Skin irritation where applied
Important warnings
- Use the lowest effective dose for the shortest necessary time.
- With a uterus, estrogen usually requires a progestogen to reduce endometrial cancer risk.
- May increase risks of blood clots, stroke, and certain cancers.
- Avoid skin contact with others until the gel is dry; wash hands after use.
Pregnancy
Not for use during pregnancy; stop and seek medical advice if pregnancy occurs.
Breastfeeding
Generally not recommended; estradiol can reduce milk production and enter breast milk.
Interactions
- Some seizure medicines and rifampicin can reduce estrogen effects.
- Some HIV medicines and St John’s wort may alter estrogen levels.
- Estrogen can affect medicines such as lamotrigine and thyroid replacement.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.