About estradiol + dydrogesterone
Combined hormone replacement therapy
Used for
- Relief of menopausal symptoms such as hot flushes and night sweats
- Prevention of bone loss after menopause in selected women
Usual adult dose
One tablet daily, following the pack sequence; prescribed dose depends on symptoms and medical history.
Common side effects
- Headache or migraine
- Breast tenderness or pain
- Nausea or abdominal discomfort
- Irregular bleeding or spotting
Important warnings
- Not for contraception; pregnancy must be excluded before starting.
- Avoid with current or previous breast cancer, unexplained vaginal bleeding, or blood clots.
- May increase risks of blood clots, stroke, and certain cancers; risk depends on individual factors and treatment duration.
- Seek urgent care for chest pain, sudden breathlessness, one-sided leg swelling, or stroke symptoms.
Pregnancy
Not for use during pregnancy. Stop treatment if pregnancy occurs and contact a healthcare professional.
Breastfeeding
Generally not recommended during breastfeeding; discuss suitable options with a healthcare professional.
Interactions
- Some seizure medicines, rifampicin, and St John’s wort may reduce hormone effects.
- Some HIV or hepatitis medicines can alter hormone levels.
- Lamotrigine levels may fall, potentially affecting seizure control.
- Tell clinicians about all medicines and supplements before treatment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.