About esomeprazole
Proton pump inhibitor
Used for
- Treats gastro-oesophageal reflux and heartburn
- Heals inflammation or ulcers caused by stomach acid
- Helps prevent ulcers with certain anti-inflammatory medicines
- Treats Helicobacter pylori infection with other medicines
Usual adult dose
Usually 20–40 mg once daily for reflux; doses vary by condition and treatment plan.
Usual dose in children
For reflux, typically 10–20 mg once daily in children aged 1–11 years; dose depends on weight and condition.
Common side effects
- Headache
- Abdominal pain, diarrhoea, constipation, or nausea
- Wind
- Long-term use may lower magnesium or vitamin B12
Important warnings
- Seek urgent care for trouble swallowing, vomiting blood, or unexplained weight loss.
- Long-term use may increase fracture, gut infection, and low-magnesium risks.
- Tell a clinician about liver problems or persistent diarrhoea.
- Granules should be prepared as directed; do not chew or crush them.
Pregnancy
Available information has not shown a clear increase in birth defects; use during pregnancy should be reviewed with a clinician.
Breastfeeding
Small amounts may enter breast milk; discuss use with a clinician, especially for a newborn or premature infant.
Interactions
- Clopidogrel: esomeprazole can reduce its antiplatelet effect.
- May affect warfarin, methotrexate, digoxin, and some HIV medicines.
- Avoid with rilpivirine-containing medicines.
- St John’s wort and rifampicin may reduce esomeprazole levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.