About esomepraz ole + vial
Proton pump inhibitor
Used for
- Treats severe reflux when tablets cannot be taken.
- Prevents stomach ulcers from certain medicines in selected patients.
- Treats bleeding stomach or duodenal ulcers after endoscopic treatment.
Usual adult dose
Usually 20–40 mg intravenously once daily; bleeding ulcers may need 80 mg, then 8 mg/hour for 72 hours.
Usual dose in children
For children aged 1 year and older: usually 10–20 mg intravenously once daily, depending on weight and condition.
Common side effects
- Headache
- Abdominal pain, diarrhoea, nausea, or constipation
- Injection-site reactions
- Low magnesium or vitamin B12 with prolonged use
Important warnings
- Use intravenous treatment only when oral treatment is not suitable; switch to oral treatment when possible.
- Seek assessment for unexplained weight loss, difficulty swallowing, vomiting blood, or black stools.
- Long-term use may increase fracture, certain infection, and nutrient-deficiency risks.
- Tell clinicians about liver disease or previous allergy to proton pump inhibitors.
Pregnancy
Use only when clinically needed; human pregnancy information is limited.
Breastfeeding
Information is limited; discuss use with a healthcare professional.
Interactions
- Clopidogrel: esomeprazole may reduce its antiplatelet effect.
- May affect warfarin, phenytoin, and medicines processed by liver enzymes.
- Avoid with nelfinavir; check before using other HIV medicines.
- May reduce absorption of medicines needing stomach acid, such as ketoconazole.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.