About ertugliflozin + sitagliptin
SGLT2 inhibitor and DPP-4 inhibitor
Used for
- Improves blood sugar control in adults with type 2 diabetes, alongside diet and exercise.
Usual adult dose
One tablet once daily, usually in the morning; dose depends on kidney function and prior treatment.
Common side effects
- Genital yeast infections
- Increased urination
- Low blood sugar, especially with insulin or sulfonylureas
- Nausea or urinary tract infections
Important warnings
- Not for type 1 diabetes or diabetic ketoacidosis.
- May cause dehydration, low blood pressure, or kidney problems.
- Rarely, can cause ketoacidosis even when blood sugar is not very high.
- Assess kidney function; it is not recommended with severe kidney impairment or dialysis.
Pregnancy
Not recommended; SGLT2 inhibitors may harm fetal kidney development, particularly in the second and third trimesters.
Breastfeeding
Not recommended because of possible effects on a nursing infant’s developing kidneys.
Interactions
- Insulin and sulfonylureas increase low blood sugar risk.
- Diuretics may increase dehydration and low blood pressure.
- Rifampin may reduce ertugliflozin exposure and effectiveness.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.