About ertugliflozin + metformin hcl
SGLT2 inhibitor and biguanide combination
Used for
- Treats type 2 diabetes alongside diet and exercise.
- Helps improve blood sugar control in adults.
Usual adult dose
Usually one tablet twice daily with meals; dose depends on current medicines and kidney function.
Common side effects
- Diarrhea, nausea, or stomach discomfort
- Genital yeast infections or urinary infections
- Increased urination
- Low blood sugar, especially with insulin or sulfonylureas
Important warnings
- Not for type 1 diabetes or diabetic ketoacidosis.
- Metformin can rarely cause life-threatening lactic acidosis, especially with severe kidney problems.
- Ertugliflozin may cause dehydration, low blood pressure, or ketoacidosis.
- Kidney function needs checking; avoid in severe impairment.
Pregnancy
Not recommended, particularly during the second and third trimesters; alternatives may be preferred.
Breastfeeding
Not recommended because effects on a nursing infant are uncertain and metformin passes into breast milk.
Interactions
- Insulin or sulfonylureas increase low blood sugar risk.
- Diuretics may increase dehydration and low blood pressure.
- Iodinated contrast procedures may require temporary interruption.
- Alcohol increases the risk of metformin-associated lactic acidosis.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.