About eplonters en
Transthyretin-directed antisense oligonucleotide
Used for
- Treats nerve damage caused by hereditary transthyretin amyloidosis in adults.
Usual adult dose
45 mg under the skin once every four weeks.
Common side effects
- Vomiting
- Injection-site reactions
- Decreased vitamin A levels
Important warnings
- Can lower vitamin A; supplementation is recommended during treatment.
- Vitamin A deficiency symptoms may occur despite supplementation.
- Not established for children or for non-hereditary transthyretin amyloidosis.
Pregnancy
Human pregnancy data are limited; potential effects on fetal development are unknown.
Breastfeeding
It is unknown whether eplontersen passes into breast milk or affects a nursing infant.
Interactions
- Vitamin A supplements may need adjustment to avoid excessive intake.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.