About epinephrin e adrenalin
Adrenergic agonist; emergency medicine
Used for
- Treats cardiac arrest during resuscitation.
- Treats severe allergic reactions (anaphylaxis), using an appropriate formulation and route.
Usual adult dose
Cardiac arrest: 1 mg intravenously or intraosseously every 3–5 minutes during resuscitation. Anaphylaxis dosing differs by route and formulation.
Usual dose in children
Cardiac arrest: 0.01 mg/kg intravenously or intraosseously every 3–5 minutes; maximum 1 mg per dose. Not for routine intramuscular anaphylaxis treatment.
Common side effects
- Fast or irregular heartbeat
- Raised blood pressure
- Tremor, anxiety, or headache
- Nausea and vomiting
Important warnings
- Intravenous use requires trained clinicians and monitoring.
- Incorrect concentration or route can cause severe harm.
- Use cautiously with heart disease or high blood pressure.
- May cause tissue damage if injected outside a vein.
Pregnancy
For life-threatening anaphylaxis or cardiac arrest, epinephrine may be used when clinically necessary; delaying treatment can be dangerous.
Breastfeeding
Limited information is available. Emergency treatment should not be delayed when needed.
Interactions
- Beta-blockers may reduce effects or cause a severe blood-pressure response.
- Tricyclic antidepressants and monoamine oxidase inhibitors may intensify cardiovascular effects.
- Other stimulants can increase heart rate and blood pressure.
- Some inhaled anesthetics increase the risk of abnormal heart rhythms.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.