About enzalutamide
Androgen receptor inhibitor
Used for
- Treats prostate cancer that has spread or is at high risk of spreading.
- Used in certain prostate cancers that have stopped responding to hormone therapy.
Usual adult dose
160 mg by mouth once daily, with or without food; swallow capsules whole.
Common side effects
- Tiredness or weakness
- Hot flushes
- High blood pressure
- Falls or fractures
Important warnings
- Can cause seizures, rarely; risk is higher with certain brain conditions or medicines.
- May cause falls, fractures, or serious heart problems.
- Can harm an unborn baby; men should use effective contraception during treatment and for three months after.
- Do not stop or change treatment without the prescriber’s direction.
Pregnancy
Not for use during pregnancy. It may harm a developing baby through exposure from a treated man’s semen.
Breastfeeding
Not used by women; breastfeeding safety has not been established.
Interactions
- Can lower levels and effectiveness of many medicines, including some blood thinners and seizure medicines.
- Some medicines can change enzalutamide levels; examples include strong enzyme inhibitors or inducers.
- Check all prescription medicines, over-the-counter products, and supplements for interactions.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.