About empagliflozin + linagliptin
SGLT2 inhibitor and DPP-4 inhibitor
Used for
- Type 2 diabetes, alongside diet and exercise, to improve blood sugar control.
Usual adult dose
Usually one tablet once daily; dosing depends on the prescribed combination and kidney function.
Common side effects
- Urinary or genital yeast infections
- Increased urination
- Low blood sugar, especially with insulin or sulfonylureas
- Joint pain or pancreatitis
Important warnings
- Not for type 1 diabetes or diabetic ketoacidosis.
- Empagliflozin can cause dehydration, low blood pressure, and ketoacidosis, sometimes with near-normal blood sugar.
- Kidney function should be assessed; linagliptin-associated heart failure has been reported.
- Seek urgent care for severe abdominal pain, vomiting, or difficulty breathing.
Pregnancy
Generally avoid, especially during the second and third trimesters; discuss alternatives with a clinician.
Breastfeeding
Not recommended while breastfeeding because of potential effects on the infant’s developing kidneys.
Interactions
- Insulin and sulfonylureas increase low-blood-sugar risk.
- Diuretics may increase dehydration and low blood pressure.
- Rifampin may reduce linagliptin effectiveness.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.