About elbasvir
Direct-acting antiviral combination
Used for
- Treats chronic hepatitis C in adults, with or without compensated cirrhosis.
- Used for hepatitis C virus genotypes 1 and 4.
Usual adult dose
One tablet by mouth once daily for 12 weeks; some genotype 1 cases require 16 weeks with ribavirin.
Common side effects
- Fatigue
- Headache
- Nausea
- Liver enzyme elevations
Important warnings
- Check for hepatitis B infection before treatment; reactivation can occur.
- Assess liver function before and during treatment; severe liver injury is possible.
- Not suitable for moderate or severe liver impairment.
- Treatment choice and duration depend on virus type and prior treatment.
Pregnancy
Pregnancy safety is not established. Ribavirin, when used, can cause birth defects and must be avoided during pregnancy.
Breastfeeding
It is unknown whether elbasvir or grazoprevir passes into breast milk; discuss risks with a clinician.
Interactions
- Rifampin, carbamazepine, phenytoin, and St John’s wort can reduce effectiveness.
- Atazanavir, darunavir, and some other HIV medicines can raise drug levels.
- Cyclosporine and some cholesterol-lowering medicines can increase adverse effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.