About elace stra nt
Estrogen receptor antagonist
Used for
- Treats advanced or metastatic breast cancer with an ESR1 mutation after hormone therapy.
Usual adult dose
345 mg by mouth once daily with food.
Common side effects
- Nausea
- High cholesterol or triglycerides
- Muscle or joint pain
- Fatigue
Important warnings
- Used for cancers with an ESR1 mutation, confirmed by an approved test.
- May cause fetal harm; effective contraception is needed during treatment and for one week afterward.
- May affect fertility; avoid breastfeeding during treatment and for one week afterward.
Pregnancy
May cause fetal harm. Avoid pregnancy during treatment and for one week after the last dose.
Breastfeeding
Do not breastfeed during treatment or for one week after the last dose.
Interactions
- Strong or moderate CYP3A4 inhibitors can increase elacestrant levels.
- Strong or moderate CYP3A4 inducers can reduce elacestrant levels.
- Elacestrant can increase levels of medicines that are CYP3A or P-glycoprotein substrates.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.