About dutasteride + tamsulosin hcl
5-alpha-reductase inhibitor and alpha blocker
Used for
- Treats enlarged prostate (benign prostatic hyperplasia) and urinary symptoms.
- May reduce the risk of urinary retention or prostate surgery.
Usual adult dose
One capsule by mouth once daily, about 30 minutes after the same meal each day.
Common side effects
- Dizziness or fainting, especially when standing
- Ejaculation problems or reduced libido
- Breast tenderness or enlargement
- Erectile dysfunction
Important warnings
- Can cause a sudden blood-pressure drop; use caution with driving until effects are known.
- May increase cataract-surgery complications; tell the eye surgeon about use.
- Can lower prostate-specific antigen (PSA) readings; clinicians should account for this during screening.
- Pregnant people should not handle leaking capsules; dutasteride can harm development of a male fetus.
Pregnancy
Not for use in pregnancy. Dutasteride may harm development of a male fetus; pregnant people should avoid contact with leaking capsules.
Breastfeeding
Not for use in women; safety during breastfeeding is not established.
Interactions
- Other alpha blockers or blood-pressure medicines can increase dizziness or fainting.
- Strong CYP3A4 inhibitors, such as ketoconazole, may raise drug levels.
- PDE-5 inhibitors, such as sildenafil, may increase low blood pressure.
- Warfarin: monitoring may be needed when starting or stopping treatment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.