About dupiluman
Interleukin-4 receptor alpha antagonist
Used for
- Moderate-to-severe atopic dermatitis
- Moderate-to-severe asthma with type 2 inflammation
- Chronic rhinosinusitis with nasal polyps
- Other selected inflammatory conditions, including prurigo nodularis
Usual adult dose
Usually 600 mg once, then 300 mg every two weeks; dose varies by condition.
Usual dose in children
For children aged 6 months and older with atopic dermatitis, dosing depends on age and weight. Asthma dosing depends on age and weight.
Common side effects
- Injection-site reactions
- Eye inflammation or irritation
- Cold sores
- Joint pain
Important warnings
- Not for sudden asthma attacks; keep prescribed rescue treatment available.
- Seek medical assessment for severe or persistent eye symptoms.
- Do not stop asthma corticosteroids suddenly without medical direction.
- Live vaccines are generally avoided during treatment.
Pregnancy
Human pregnancy data are limited; use depends on weighing potential benefits and risks.
Breastfeeding
It is unknown whether dupilumab enters breast milk; discuss benefits and potential risks with a clinician.
Interactions
- Live vaccines may be less safe or effective during treatment.
- No major interactions with common medicines are established; review all treatments with a clinician.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.