About dupilumab
Interleukin-4 receptor alpha antagonist
Used for
- Atopic dermatitis (eczema)
- Asthma and certain chronic sinus conditions
- Eosinophilic esophagitis
- Prurigo nodularis
Usual adult dose
Usually 300 mg every two weeks for eczema; other conditions use different schedules and may require a loading dose.
Usual dose in children
For eligible children, dosing depends on age, weight, and condition; schedules range from every two to four weeks.
Common side effects
- Injection-site reactions
- Eye inflammation or irritation
- Cold sores
- Joint pain
Important warnings
- Seek urgent care for severe allergic reactions.
- New or worsening eye symptoms may need medical assessment.
- Do not stop asthma medicines abruptly when starting treatment.
- Live vaccines are generally avoided during treatment.
Pregnancy
Human pregnancy information is limited; use when expected benefits outweigh potential risks.
Breastfeeding
It is unknown whether dupilumab passes into breast milk; discuss potential risks and benefits with a clinician.
Interactions
- Live vaccines may be less safe or effective.
- Dupilumab may affect levels of some medicines processed by CYP enzymes; monitoring may be needed.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.