About droperidol
Butyrophenone antipsychotic and antiemetic
Used for
- Prevention or treatment of nausea and vomiting after surgery
- Treatment of severe agitation in some monitored settings
Usual adult dose
For postoperative nausea, commonly 0.625–1.25 mg intravenously once; doses vary by indication and local guidance.
Usual dose in children
For postoperative nausea in children, commonly 10–15 micrograms/kg intravenously once; specialist guidance is needed.
Common side effects
- Drowsiness or dizziness
- Low blood pressure
- Restlessness or muscle stiffness
- Abnormal heart rhythm
Important warnings
- Can prolong the QT interval and cause serious arrhythmias; ECG monitoring may be required.
- Avoid with prolonged QT, significant electrolyte abnormalities, or certain heart conditions.
- May cause severe drowsiness, movement disorders, or neuroleptic malignant syndrome.
- Given by injection under medical supervision.
Pregnancy
Use only when clearly needed; human pregnancy data are limited, and newborn effects are possible with use near delivery.
Breastfeeding
Breastfeeding safety information is limited; seek clinical guidance, especially after repeated doses.
Interactions
- Other QT-prolonging medicines increase abnormal-heart-rhythm risk.
- Sedatives, opioids, and alcohol can increase drowsiness and breathing impairment.
- Medicines that lower potassium or magnesium may increase rhythm risks.
- Dopamine agonists may have reduced effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.