About doxapram hydrochloride
Respiratory stimulant
Used for
- Short-term treatment of drug-induced respiratory depression after general anesthesia
- Temporary support of breathing in selected cases of acute respiratory failure
Usual adult dose
By slow intravenous injection or infusion, commonly 1–2 mg/kg initially; further dosing depends on response and product guidance.
Common side effects
- Restlessness or agitation
- Nausea and vomiting
- Raised blood pressure or fast heartbeat
- Muscle twitching or seizures
Important warnings
- Requires close monitoring of breathing, blood pressure, and heart rhythm.
- Does not replace airway support or treatment of the underlying cause.
- May be unsuitable with seizure disorders, severe heart disease, or high blood pressure.
- Use only in settings equipped to manage serious reactions.
Pregnancy
Use only when clearly needed; human pregnancy safety information is limited.
Breastfeeding
Information is limited; whether it passes into breast milk is unclear.
Interactions
- Stimulants or medicines that lower the seizure threshold may increase seizure risk.
- Monoamine oxidase inhibitors may intensify cardiovascular effects.
- Other medicines affecting blood pressure or heart rhythm may increase risks.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.