About domperidone tablets
Dopamine-blocking anti-nausea medicine
Used for
- Short-term relief of nausea and vomiting
Usual adult dose
Usually 10 mg up to three times daily, before meals; use the lowest effective dose for the shortest time.
Common side effects
- Dry mouth
- Headache
- Abdominal cramps
- Raised prolactin, sometimes causing breast changes
Important warnings
- Can cause serious abnormal heart rhythms, especially at higher doses.
- Risk is greater with heart disease, older age, or certain interacting medicines.
- Avoid in moderate or severe liver problems, gastrointestinal bleeding, or bowel obstruction.
- Use is generally limited to one week.
Pregnancy
Use only if clearly needed; safety information is limited.
Breastfeeding
Small amounts enter breast milk; generally avoid unless a clinician considers it necessary.
Interactions
- Some antibiotics and antifungals, including clarithromycin and ketoconazole, increase heart-rhythm risk.
- Avoid with medicines that prolong the QT interval or strongly inhibit CYP3A4.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.