About dolutegra vir sodium
HIV integrase strand transfer inhibitor
Used for
- Used with other HIV medicines to treat HIV-1 infection.
- May be used for HIV prevention after exposure, with other medicines.
Usual adult dose
Usually 50 mg once daily; sometimes 50 mg twice daily with certain medicines or resistance.
Usual dose in children
For children weighing at least 20 kg: dose depends on weight and other medicines; 50 mg may be once daily.
Common side effects
- Headache
- Trouble sleeping
- Nausea or diarrhea
- Weight gain
Important warnings
- Can cause serious allergic reactions or liver problems.
- May worsen hepatitis B or C liver disease.
- Mood changes, including depression, have been reported.
- Do not stop other HIV medicines without medical guidance.
Pregnancy
Generally used in pregnancy to treat HIV; treatment decisions depend on clinical circumstances.
Breastfeeding
HIV can pass through breast milk; recommendations depend on local guidance and individual circumstances.
Interactions
- Dofetilide must not be combined with dolutegravir.
- Rifampin and some seizure medicines can lower dolutegravir levels.
- Separate from antacids or supplements containing aluminum, magnesium, calcium, or iron as directed.
- Metformin levels may rise; dose monitoring may be needed.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.