About disopyramide phosphate
Class IA antiarrhythmic
Used for
- Treats certain serious abnormal heart rhythms, including ventricular arrhythmias.
- May be used for selected supraventricular arrhythmias.
Usual adult dose
Usually 100–150 mg every 6 hours; dosing depends on the rhythm and kidney function.
Common side effects
- Dry mouth, constipation, blurred vision, and difficulty urinating.
- Dizziness, nausea, or fatigue.
- Low blood pressure or worsening heart failure.
- Serious abnormal heart rhythms, including QT prolongation.
Important warnings
- Can cause dangerous rhythm changes; ECG and electrolyte monitoring may be needed.
- May worsen heart failure or cause low blood pressure.
- Use cautiously with glaucoma, urinary retention, or myasthenia gravis.
- Dose adjustment may be needed with kidney or liver problems.
Pregnancy
Use only when clearly needed; human pregnancy information is limited.
Breastfeeding
Avoid or use only with medical guidance; information about transfer into milk is limited.
Interactions
- Other QT-prolonging medicines increase serious rhythm risks.
- Medicines that slow heart rate or affect heart rhythm may increase complications.
- Anticholinergic medicines can worsen constipation, blurred vision, or urinary retention.
- Some medicines affecting kidney function or drug metabolism may alter disopyramide levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.