About disodium fosfomycin
Phosphonic acid antibiotic
Used for
- Severe bacterial infections caused by susceptible bacteria, usually when other antibiotics are unsuitable.
- Often used with another antibiotic to help limit resistance.
Usual adult dose
Commonly 12–24 g daily by intravenous infusion, divided into 2–4 doses; specialist dosing depends on infection and kidney function.
Usual dose in children
Usually 100–200 mg/kg daily by intravenous infusion, divided into 2–4 doses; specialist dosing depends on infection and kidney function.
Common side effects
- Low blood potassium
- High blood sodium or fluid overload
- Diarrhoea, nausea, or vomiting
- Infusion-site irritation or allergic reactions
Important warnings
- Use only for serious infections under specialist supervision.
- Monitor kidney function, electrolytes, and fluid balance during treatment.
- High sodium content may worsen heart failure or high blood pressure.
- Adjust dosing for reduced kidney function; severe allergy is possible.
Pregnancy
Human pregnancy information is limited. Use only when a clinician judges treatment necessary.
Breastfeeding
Information is limited; discuss use with a clinician, especially when treating a newborn.
Interactions
- May increase potassium loss with corticosteroids or some diuretics.
- Can affect blood-thinning medicines such as warfarin; monitoring may be needed.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.