About diroximel fumarate
Fumaric acid ester disease-modifying therapy
Used for
- Treats relapsing forms of multiple sclerosis in adults.
Usual adult dose
Take 231 mg twice daily for seven days, then 462 mg twice daily. Swallow capsules whole.
Common side effects
- Flushing, warmth, itching, or rash
- Nausea, vomiting, diarrhoea, or stomach pain
- Reduced lymphocyte counts
- Increased liver enzymes
Important warnings
- Blood tests monitor lymphocytes and liver function before and during treatment.
- Rare progressive multifocal leukoencephalopathy can occur, especially with prolonged low lymphocyte counts.
- Serious infections, including herpes zoster, have been reported.
- Do not use with dimethyl fumarate or if allergic to diroximel fumarate.
Pregnancy
Human pregnancy information is limited. Discuss potential risks with a clinician; treatment is generally avoided during pregnancy unless needed.
Breastfeeding
It is unknown whether diroximel fumarate passes into breast milk. Discuss treatment and breastfeeding risks with a clinician.
Interactions
- Avoid other fumarate-containing medicines, including dimethyl fumarate.
- Medicines that suppress the immune system may increase infection risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.