About dihydroergotamine mysilate
Ergot-derived antimigraine medicine
Used for
- Acute treatment of migraine attacks
- Acute treatment of cluster headache in some settings
Usual adult dose
Migraine: 1 mg by injection; may repeat after 1 hour. Maximum 2 mg per attack and 6 mg weekly.
Common side effects
- Nausea and vomiting
- Dizziness or tingling
- Injection-site pain
- Muscle cramps
Important warnings
- Not for preventing headaches or treating ordinary headaches.
- Avoid in pregnancy, uncontrolled high blood pressure, or vascular disease.
- Do not use within 24 hours of triptans or other ergot medicines.
- Seek urgent care for chest pain, numbness, or cold, pale limbs.
Pregnancy
Avoid; it can cause uterine contractions and harm the fetus.
Breastfeeding
Avoid; it may reduce milk production and could harm the infant.
Interactions
- Triptans and other ergot medicines increase serious blood-vessel risks.
- Strong CYP3A4 inhibitors, including clarithromycin and ritonavir, can cause dangerous toxicity.
- Avoid with other vasoconstrictors, including some decongestants.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.