About digoxin
Cardiac glycoside
Used for
- Heart failure symptom control
- Heart-rate control in atrial fibrillation
Usual adult dose
IV loading: 0.5–1 mg total, divided doses. Maintenance: typically 0.125–0.25 mg daily; individualized.
Usual dose in children
Individualized by age, weight, kidney function, and heart condition; specialist dosing required.
Common side effects
- Nausea, vomiting, or loss of appetite
- Slow or irregular heartbeat
- Dizziness, confusion, or weakness
- Blurred or yellow-tinted vision
Important warnings
- Toxicity can occur, especially with kidney impairment or low potassium.
- Blood levels and kidney function may need monitoring.
- Use cautiously with heart block or certain abnormal heart rhythms.
- Injection should be administered by a healthcare professional.
Pregnancy
May be used when needed under medical supervision; dosing and monitoring may require adjustment.
Breastfeeding
Passes into breast milk in small amounts; generally considered compatible with breastfeeding at prescribed doses.
Interactions
- Amiodarone, verapamil, and quinidine can raise digoxin levels.
- Some antibiotics, including clarithromycin, can increase toxicity risk.
- Diuretics that lower potassium can increase digoxin-related heart risks.
- Antacids and some fiber supplements can reduce absorption of oral digoxin.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.