About diacerein
Symptomatic slow-acting osteoarthritis medicine
Used for
- Relief of symptoms in osteoarthritis, particularly of the hip or knee.
Usual adult dose
Usually 50 mg twice daily with meals; treatment may start once daily for two to four weeks.
Common side effects
- Diarrhea, sometimes severe
- Abdominal pain
- Dark yellow or brown urine
- Raised liver enzymes
Important warnings
- Can cause severe diarrhea and dehydration.
- Rarely causes liver injury; avoid with liver disease.
- Not recommended for people aged 65 years or older in some regions.
- Benefit may take several weeks to appear.
Pregnancy
Generally not recommended during pregnancy because safety is insufficiently established.
Breastfeeding
Generally not recommended during breastfeeding; effects on nursing infants are uncertain.
Interactions
- Avoid combining with laxatives or other medicines that cause diarrhea.
- Antacids may reduce absorption; separate doses by at least two hours.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.