About dextran sodium chloride
Colloid plasma volume expander
Used for
- Short-term plasma volume expansion during shock or significant blood loss
- Improving blood flow in certain surgical settings
Usual adult dose
Intravenous dose is individualized; commonly up to 1,000 mL on the first day, then lower amounts if needed.
Common side effects
- Fluid overload and breathing difficulty
- Allergic reactions, rarely severe
- Bleeding or impaired blood clotting
- Kidney injury
Important warnings
- Must be given intravenously under medical supervision.
- Avoid in severe kidney disease, heart failure, or fluid overload.
- Can increase bleeding risk and interfere with blood typing and crossmatching.
- Rare severe allergic reactions can occur; treatment must be available.
Pregnancy
Use only when clearly needed; safety depends on the clinical situation.
Breastfeeding
Information is limited; use depends on clinical need.
Interactions
- Anticoagulants and medicines that increase bleeding risk may worsen bleeding.
- May interfere with laboratory blood typing and crossmatching.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.