About dextran sodium chloride
Colloid plasma volume expander
Used for
- Short-term treatment of low circulating blood volume when appropriate.
- Improving blood flow in selected circulation disorders or during surgery.
Usual adult dose
Dose and infusion rate depend on the condition and body weight; given by intravenous infusion under close medical supervision.
Usual dose in children
Not routinely used in children; specialist dosing is required.
Common side effects
- Allergic reactions, sometimes severe
- Fluid overload or heart failure
- Bleeding or impaired blood clotting
- Kidney injury
Important warnings
- Can cause severe allergic reactions; infusion requires close monitoring.
- Use cautiously with heart or kidney problems, bleeding disorders, or dehydration.
- May affect blood clotting and interfere with blood compatibility testing.
- Avoid in severe heart failure, marked kidney impairment, or active bleeding.
Pregnancy
Use only when clearly needed; safety information is limited, and risks depend on the clinical situation.
Breastfeeding
Effects on breastfeeding are not well established; use only when clinically necessary.
Interactions
- Anticoagulants and antiplatelet medicines may increase bleeding risk.
- Other fluids or medicines that increase fluid load may raise overload risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.