About desvenlafaxine
Serotonin-norepinephrine reuptake inhibitor (SNRI)
Used for
- Treatment of major depressive disorder in adults
Usual adult dose
Usually 50 mg once daily, with or without food; swallow whole.
Common side effects
- Nausea, dizziness, dry mouth, constipation
- Sweating, reduced appetite, sleep problems
- Sexual side effects
- Increased blood pressure
Important warnings
- May increase suicidal thoughts, especially in young adults.
- Do not stop suddenly; withdrawal symptoms can occur.
- Can cause serotonin syndrome, abnormal bleeding, or low blood sodium.
- Screen for bipolar disorder; may trigger mania.
Pregnancy
Use during pregnancy only when benefits outweigh risks; late-pregnancy exposure may cause newborn complications.
Breastfeeding
Passes into breast milk; infant effects are possible. Discuss risks and benefits with a clinician.
Interactions
- MAO inhibitors: dangerous reactions; require a washout period.
- Other serotonergic medicines, including tramadol or triptans, increase serotonin syndrome risk.
- NSAIDs, aspirin, and anticoagulants may increase bleeding risk.
- Alcohol may worsen side effects; avoid or limit use.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.