About desmopressin acetate
Synthetic antidiuretic hormone
Used for
- Central diabetes insipidus
- Bedwetting at night
- Frequent nighttime urination in adults
Usual adult dose
Diabetes insipidus: usually 0.1–0.2 mg three times daily. Nighttime urination: usually 0.1 mg at bedtime, adjusted by a clinician.
Usual dose in children
Bedwetting: usually 0.2 mg at bedtime; may be increased under medical supervision. For children aged six years and older.
Common side effects
- Headache
- Nausea or stomach pain
- Dizziness
- Fluid retention and low blood sodium
Important warnings
- Can cause dangerously low blood sodium; follow fluid restrictions prescribed for the condition.
- Seek urgent care for confusion, severe headache, vomiting, unusual tiredness, or seizures.
- Avoid or use only with specialist guidance in significant kidney or heart disease.
- Do not use for bedwetting during illnesses causing fever, vomiting, or diarrhea.
Pregnancy
Use only when clearly needed and prescribed; discuss risks and benefits with a healthcare professional.
Breastfeeding
Small amounts may enter breast milk; use with medical guidance.
Interactions
- Some antidepressants, including SSRIs, increase low-sodium risk.
- NSAIDs such as ibuprofen can increase water retention and low-sodium risk.
- Carbamazepine and some other medicines may increase desmopressin effects.
- Lithium and demeclocycline can reduce its antidiuretic effect.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.