About desmopressin acetate
Antidiuretic hormone analogue
Used for
- Central diabetes insipidus
- Bedwetting in selected patients, where nasal use is approved
Usual adult dose
Central diabetes insipidus: usually 10–40 micrograms daily, divided into one or two doses; individualize.
Usual dose in children
Central diabetes insipidus: dose is individualized by age and response; nasal treatment is generally avoided for bedwetting.
Common side effects
- Headache
- Nasal congestion or irritation
- Nausea
- Water retention and low blood sodium
Important warnings
- Excess fluid intake can cause dangerously low blood sodium.
- Nasal use for bedwetting is restricted or avoided in many regions.
- Monitor blood sodium when clinically indicated, especially during prolonged treatment.
- Nasal congestion or scarring may make absorption unpredictable.
Pregnancy
Use only when clinically necessary; pregnancy data are limited, and specialist monitoring may be needed.
Breastfeeding
Small amounts may enter breast milk; clinically important effects in infants are unlikely.
Interactions
- Medicines increasing low-sodium risk, including some antidepressants and carbamazepine
- NSAIDs, which may increase water retention
- Other medicines affecting fluid balance or blood sodium
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.