About desflurane
Volatile inhaled general anesthetic
Used for
- Induction and maintenance of general anesthesia in adults
- Maintenance of general anesthesia in children
Usual adult dose
Given by an anesthesia professional using a calibrated vaporizer; concentration is adjusted to the patient and procedure.
Usual dose in children
Maintenance only, typically 5.2–10% inhaled concentration; not recommended for induction in children.
Common side effects
- Cough, breath-holding, or airway irritation
- Nausea and vomiting
- Low blood pressure or fast heart rate
- Rare malignant hyperthermia
Important warnings
- Can cause life-threatening malignant hyperthermia in susceptible people.
- May impair breathing and circulation; requires continuous monitoring by anesthesia professionals.
- Can increase potassium and cause dangerous heart rhythms, especially in children with certain muscle disorders.
- May trigger agitation or breathing complications during recovery, particularly in children.
Pregnancy
Use only when general anesthesia is necessary; human pregnancy safety data are limited.
Breastfeeding
Anesthesia providers generally advise resuming breastfeeding once the parent is awake and able to feed; confirm with the care team.
Interactions
- Other anesthetics, opioids, and sedatives can increase breathing and blood pressure effects.
- Succinylcholine increases the risk of malignant hyperthermia and dangerous potassium elevation.
- Beta blockers may increase the risk of low blood pressure or slow heart rate.
- Epinephrine and other sympathomimetics may increase heart rhythm risks.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.