About desferrioxamine
Iron-chelating agent
Used for
- Treats iron overload from repeated blood transfusions.
- Treats acute iron poisoning.
- May help diagnose certain iron-storage disorders.
Usual adult dose
Iron overload: usually 20–60 mg/kg daily by slow infusion. Acute poisoning: specialist-directed intravenous treatment.
Usual dose in children
Iron overload: usually 20–40 mg/kg daily by slow infusion. Acute poisoning: specialist-directed intravenous treatment.
Common side effects
- Injection-site pain or swelling
- Low blood pressure, especially with rapid infusion
- Vision or hearing changes
- Allergic reactions
Important warnings
- Dose and infusion speed require careful medical supervision.
- Long-term treatment can affect hearing, vision, growth, and bone development.
- Kidney problems and serious infections have been reported.
- Avoid or use specialist guidance with severe kidney disease.
Pregnancy
Use only when clearly needed; treatment decisions require specialist assessment.
Breastfeeding
Breastfeeding safety is uncertain; specialist assessment is needed.
Interactions
- Vitamin C can increase iron excretion but may raise heart risks.
- May affect tests measuring aluminium or iron.
- Prochlorperazine may cause temporary movement or coordination problems when used together.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.