About deflazacort
Glucocorticoid corticosteroid
Used for
- Treats inflammatory and autoimmune conditions
- Used for Duchenne muscular dystrophy in some countries
Usual adult dose
Varies by condition; commonly 6–90 mg daily, taken once or in divided doses.
Usual dose in children
For Duchenne muscular dystrophy: 0.9 mg/kg once daily. Other uses require condition-specific dosing.
Common side effects
- Increased appetite and weight gain
- Mood changes or trouble sleeping
- Stomach upset
- Higher infection risk
Important warnings
- Long-term use can weaken bones and suppress growth in children.
- Do not stop long-term treatment suddenly; doses usually need gradual reduction.
- May raise blood sugar and blood pressure.
- Avoid live vaccines during immunosuppressive treatment.
Pregnancy
Use only when clearly needed; prolonged or high-dose treatment may affect fetal growth or newborn adrenal function.
Breastfeeding
Small amounts may enter breast milk; prolonged or high doses may affect the infant or milk production.
Interactions
- Rifampicin, phenytoin, and carbamazepine may reduce its effects.
- Strong CYP3A4 inhibitors, including ritonavir, may increase exposure.
- NSAIDs may increase stomach ulcer or bleeding risk.
- Warfarin effects may change; monitoring may be needed.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.