About deflazaco rt
Corticosteroid
Used for
- Duchenne muscular dystrophy
- Inflammatory and autoimmune conditions
- Severe allergic conditions
Usual adult dose
Duchenne muscular dystrophy: 0.9 mg/kg once daily. Other conditions: dose varies by disease and response.
Usual dose in children
Duchenne muscular dystrophy, ages 2 years and older: 0.9 mg/kg once daily.
Common side effects
- Increased appetite and weight gain
- Mood changes and difficulty sleeping
- Raised blood sugar and blood pressure
- Bone thinning and increased infection risk
Important warnings
- Sudden stopping after prolonged use can cause adrenal insufficiency.
- May mask infections and worsen existing infections.
- Avoid live vaccines during immunosuppressive treatment.
- Prolonged use may cause cataracts, glaucoma, and slowed childhood growth.
Pregnancy
Use only when benefits outweigh risks; prolonged treatment may affect fetal growth and newborn adrenal function.
Breastfeeding
Breastfeeding data are limited. Corticosteroids may enter breast milk; prolonged high doses could affect infant growth and adrenal function.
Interactions
- Clarithromycin and azole antifungals can increase deflazacort exposure.
- Rifampicin, carbamazepine, and phenytoin can reduce effectiveness.
- NSAIDs increase stomach ulcer and bleeding risk.
- Live vaccines may cause infection during immunosuppressive treatment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.