About deferipro ne
Iron-chelating agent
Used for
- Treats iron overload from repeated blood transfusions, especially in thalassemia.
Usual adult dose
Usually 75 mg/kg daily by mouth, divided into three doses; specialist-guided adjustment is required.
Usual dose in children
Usually 75 mg/kg daily by mouth, divided into three doses, for children aged 8 years and older.
Common side effects
- Nausea, vomiting, abdominal pain, or diarrhea
- Joint pain
- Increased liver enzymes
- Low white blood cells, including severe neutropenia or agranulocytosis
Important warnings
- Regular blood tests are required to monitor neutrophil counts and liver function.
- Stop treatment and seek urgent assessment for fever or infection symptoms.
- Use only with specialist supervision; monitor iron levels and kidney function.
- Do not combine with other iron chelators unless directed by a specialist.
Pregnancy
May harm the fetus; avoid during pregnancy. Effective contraception is recommended during treatment and for six months afterward.
Breastfeeding
Breastfeeding is not recommended during treatment and for two weeks after the last dose.
Interactions
- Avoid medicines that can lower neutrophil counts, if possible.
- Antacids containing aluminum may increase aluminum exposure.
- Zinc supplements may reduce zinc levels; monitoring may be needed.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.