About darunavir amorphou s
HIV protease inhibitor
Used for
- Treatment of HIV-1 infection, combined with other HIV medicines.
Usual adult dose
Usually 600 mg twice daily with ritonavir 100 mg, with food; dosing depends on treatment history and resistance.
Usual dose in children
For children aged 3 years and older, dose is based on weight and must be combined with ritonavir and food.
Common side effects
- Diarrhoea, nausea, vomiting, or abdominal pain
- Rash
- Headache
- Raised liver enzymes or cholesterol
Important warnings
- Must be taken with ritonavir and other HIV medicines.
- Serious skin reactions and liver problems can occur.
- May worsen diabetes or affect blood sugar.
- Do not stop or change treatment without medical guidance.
Pregnancy
Use during pregnancy only under specialist guidance; dosing and monitoring may need adjustment.
Breastfeeding
People with HIV are generally advised not to breastfeed, to prevent transmission of HIV.
Interactions
- Many medicines interact, including rifampicin, St John’s wort, and some seizure medicines.
- Can interact with blood thinners, cholesterol medicines, and erectile dysfunction medicines.
- Ritonavir affects many medicines; a pharmacist should check all medicines and supplements.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.